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SYBR® Green I as a biomarker for schizophrenia

Davood Zaeifi, Mehdi Rahmati, Vahab Piranfar, Islamic Azad University of Tonekabon

Date Posted: Wednesday, June 10, 2009

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The purpose of this study were to examine if the mRNA of the peripheral dopamine receptor is changed in schizophrenia patients.
50 Naive patients were enrolled. After extracting RNA from white blood cells, cDNA is synthesized.
After doing the quantitative Real-time PCR, expression of D3 receptors in healthy persons and patients were compared.
Results of this examinations reveals that expression of D3 receptor is increased in compared with controls sample.

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